Synthetic antigen mimetics matrices immuno-reactive with...

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 1/00 (2006.01) C07K 7/08 (2006.01) C07K 14/00 (2006.01) C07K 14/47 (2006.01) C40B 30/04 (2006.01) C40B 40/10 (2006.01) G01N 33/564 (2006.01)

Patent

CA 2641448

A 3D matrix of selected, synthetic peptide mimic sequences is disclosed that are preferentially recognized by auto-antibodies, specifically by autoimmune antibodies to be detected in patients afflicted with rheumatic arthritis, enabling enhanced sensitivity and specificity in detection of these anti-bodies in pre--symptomatic patients, in patients showing symptoms as well as patients confirmed positive for rheumatoid arthritis.

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