Synthetic antigenic composition and process for making same

Details Synthetic antigenic composition and process for making same Synthetic antigenic composition and process for making same

A - Human Necessities

61

K

167/129, 167/37,

A61K 39/39 (2006.01) A61K 39/385 (2006.01) C07K 14/02 (2006.01) G01N 33/577 (2006.01)

Patent

CA 1206094

ABSTRACT OF THE DISCLOSURE This invention relates to a synthetic vaccine and to a process for its preparation. More especially, this invention relates to a method of determining the antigenic or allergenic determinants of protein antigens or allergens and on the basis of the determination of the point of greatest local average hydrophilicity of such protein antigens or allergens, forming a synthetic vaccine containing a designated sequence of six amino acids corresponding to the point of greatest local average hydrophilicity. Thus, the invention relates to the determination of the antigenic or allergenic determinants and on the basis of such information, the formation of synthetic vaccines which provide a protective immunological response or a decrease in allergen sensitivity as the case may be.

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