C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 7/06 (2006.01) A61K 31/70 (2006.01) C07H 5/04 (2006.01) C07H 5/06 (2006.01) C07H 7/00 (2006.01) C07H 15/10 (2006.01)
Patent
CA 2493690
The invention is directed to compounds of formula (I) wherein X is O, OR NH; R~ is a hydrocarbon chain; R3 andR4 are hydrogen, OH or a monosaccharide; R5 is hydrogen or a monosaccharide; Q~ is optionally present and may be a C1-10 hydrocarbon; X~ is optionally present and may be O, S or NR8; and Q3 may be a hydrocarbon or hydrogen. The invention is also directed to the use of the compounds for treating cancer, infectious diseases and autoimmune diseases. The invention is also directed to syntheses of the compounds of formula (I).
L'invention concerne les composés représentés par la formule (I) , dans laquelle X représente O, OR NH; R~ représente une chaîne hydrocarbure; R?3¿ et R?4¿ représentent l~hydrogène, OH ou un monosaccharide; R?5¿ représente l'hydrogène ou un monosaccharide; Q~ est facultatif et peut être un hydrocarbure C¿1-10?; X~ est également facultatif et peut représenter O, S or NR?8¿; et Q?3¿ peut représenter un hydrocarbure ou l'hydrogène. L~invention concerne également l~utilisation de ces composés pour le traitement du cancer, des maladies infectieuses et des maladies auto-immunes. L~invention porte en outre sur la synthèse des composé représentés par la formule (I).
Chen Guangwu
Franck Richard W.
Tsuji Moriya
Yang Guangli
New York University
Robic
The Research Foundation Of The City University Of New York
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