Synthetic catalytic free radical scavengers useful as...

C - Chemistry – Metallurgy – 07 – F

Patent

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C07F 13/00 (2006.01) A61K 31/28 (2006.01) A61K 31/555 (2006.01) B01J 31/22 (2006.01) C07C 251/24 (2006.01) C07F 1/08 (2006.01) C07F 9/00 (2006.01) C07F 11/00 (2006.01) C07F 15/00 (2006.01)

Patent

CA 2223510

The invention provides antioxidant salen-metal complexes, compositions of such antioxidant salen-metal complexes having superoxide activity, catalase activity, and/or peroxidase activity, compositions of salen- metal complexes in a form suitable for pharmaceutical administration to treat or prevent a disease associated with cell or tissue damage produced by free radicals such as superoxide, and cosmetic and free radical quenching formulations of salen metal compounds.

L'invention concerne des complexes antioxydants salène-métal, des compositions de ces complexes antioxydants salène-métal ayant une activité de superoxyde, de catalase et/ou de peroxydase, des compositions de complexes salène-métal se présentant sous une forme appropriée à l'administration pharmaceutique, pour traiter et prévenir une maladie associée à des lésions cellulaires ou tissulaires dues à des radicaux libres tels que des superoxydes, ainsi que des formulations cosmétiques de composés salène-métal qui détruisent les radicaux libres.

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