Synthetic compounds having two epitopes in immunoassay

Details Synthetic compounds having two epitopes in immunoassay Synthetic compounds having two epitopes in immunoassay

C - Chemistry, Metallurgy

07

K

C07K 17/02 (2006.01) C07K 7/06 (2006.01) C07K 14/47 (2006.01) G01N 33/531 (2006.01) G01N 33/68 (2006.01) C07K 7/64 (2006.01)

Patent

CA 2382035

The invention concerns the use of at least a synthetic compound comprising: a carrier molecule having at least a hydrocarbon chain comprising at least 10, advantageously at least 12, preferably at least 14 and not more than 300, advantageously not more than 100, preferably not more than 50, selected among C, N, O, S, P and Si, and comprising at least two reactive functions, or capable of reacting, for grafting lateral arms on said chain, and at least two different epitopes carried by said lateral arms grafted on said carrier molecule, as standard or control for immnuoassay of said biological molecules, in particular of polypeptides or proteins.

Cette invention concerne l'utilisation d'au moins un composé synthétique comprenant: une molécule porteuse possédant une chaîne hydrocarbonée ayant au moins 10, avantageusement au moins 12, de préférence au moins 14 et au plus 300, avantageusement au plus 100, de préférence au plus 50 atomes choisis parmi C, N, O, S, P et Si, et comprenant au moins deux fonctions réactives, ou susceptibles de réagir, permettant le greffage de bras latéraux sur ladite chaîne; et au moins deux épitopes différents portés par lesdits bras latéraux greffés sur ladite molécule porteuse, comme étalon ou témoin pour des immuno-dosages de molécules biologiques, notamment de polypeptides ou protéines.

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