Synthetic cornea from retinal stem cells

Details Synthetic cornea from retinal stem cells Synthetic cornea from retinal stem cells

C - Chemistry, Metallurgy

12

N

C12N 5/071 (2010.01) A61L 27/38 (2006.01) C12N 15/00 (2006.01) C12Q 1/02 (2006.01) A61F 2/14 (2006.01)

Patent

CA 2658813

Methods of producing synthetic corneas are disclosed which are differentiated from retinal stem cells (rSC) derived from parthenogenetically activated human oocytes, including that such synthetic corneas are produced in the absence of a 3-D scaffold. Isolated synthetic corneas, produced by the disclosed methods, are also described.

La présente invention concerne des procédés de production de cornées synthétiques, lesquelles sont différenciées de cellules souches rétiniennes (CSR) dérivées d'ovocytes humains obtenus par activation parthénogénétique. Lesdits procédés consistent à produire de telles cornées synthétiques en l'absence de support en 3D. La présente invention concerne également des cornées synthétiques isolées, produites par les procédés décrits.

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