Synthetic hiv protease gene and method for its expression

C - Chemistry – Metallurgy – 12 – N

Patent

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1/33, 195/1.235,

C12N 15/57 (2006.01) C12N 9/50 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1340748

The invention is a synthetic DNA sequence for encoding a specific enzyme or protease. The protease is essential for the completion (replication) of an infective human immunodeficiency virus (HIV). The invented gene is desirable for the expression of the protease by recombinant methodology in prokaryotic and/or eukanotic cells and the production of a commercially desirable amount of the protease for biochemical and physical characterization, necessary to find effective inhibitor of the protease, and thereby to block the production of infectious human immunodeficiency virus (HIVs).

604978

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