C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/11 (2006.01) A01K 67/027 (2006.01) C12N 5/10 (2006.01) C12N 15/10 (2006.01) C12N 15/64 (2006.01) C12N 15/67 (2006.01) C12N 15/79 (2006.01) C12N 15/85 (2006.01)
Patent
CA 2398541
Synthetic and isolated translational regulatory elements, including oligonucleotides that have translational enhancing activity, internal ribosome entry site (IRES) activity, or translational inhibitory activity, and multimers of such translational regulatory elements are provided. In addition, compositions that include such translational regulatory elements are provided, as are methods of using the translational regulatory elements.
L'invention concerne d'une part, des éléments de régulation de la traduction isolés de synthèse, notamment des oligonucléotides possédant une activité favorisant la traduction, une activité de site d'entrée interne du ribosome (IRES), ou une activité empêchant la traduction, et d'autre part, des multimères desdits éléments de régulation de la traduction. En outre, l'invention concerne des compositions renfermant ces éléments de régulation de la traduction, ainsi que des procédés d'utilisation desdits éléments.
Chappell Stephen A.
Edelman Gerald M.
Krushel Leslie
Mauro Vincent P.
Owens Geoffrey
Mbm Intellectual Property Law Llp
The Scripps Research Institute
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