Synthetic membrane anchors

Details Synthetic membrane anchors Synthetic membrane anchors

C - Chemistry, Metallurgy

07

H

C07H 15/04 (2006.01) C12N 5/078 (2010.01) A61K 31/7028 (2006.01) C07F 9/117 (2006.01)

Patent

CA 2560781

The invention relates to synthetic molecules that spontaneously and stably incorporate into lipid by-layers, including cell membranes. Particularly, although not exclusively, the invention relates to the use of these molecules as synthetic membrane anchors or synthetic molecule constructs to effect qualitative and quantitative changes in the expression of cell surface antigens.

La présente invention concerne des molécules de synthèse qui s'incorporent spontanément et de façon stable à des bicouches lipidiques, comprenant des membranes cellulaires. L'invention concerne en particulier, mais pas exclusivement, l'utilisation de ces molécules comme éléments d'ancrage de membranes synthétiques ou molécules hybrides synthétiques, pour produire des modifications qualitatives et quantitatives de l'expression d'antigènes de surface cellulaire.

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