Synthetic method for fluoromethylation of halogenated alcohols

Details Synthetic method for fluoromethylation of halogenated alcohols Synthetic method for fluoromethylation of halogenated alcohols

C - Chemistry, Metallurgy

07

C

C07C 43/12 (2006.01) C07C 41/16 (2006.01) C07C 41/22 (2006.01) C07C 41/28 (2006.01) C07C 41/52 (2006.01) C07C 43/313 (2006.01)

Patent

CA 2410381

A method for fluoromethylation of a halogenated alcohol. The method includes refluxing a halogenated alcohol with a dihalomethane under basic conditions in a first solvent to form a halomethyl ether and fluorinating the halomethyl ether in the presence of a fluorinating agent.

L'invention concerne un procédé de fluorométhylation d'un alcool halogéné. Ce procédé consiste à chauffer à reflux un alcool halogéné avec un dihalométhane dans des conditions de base dans un premier solvant pour former un éther d'halométhyle, et à fluorer l'éther d'halométhyle en présence d'un agent de fluoration.

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