Synthetic methods for the preparation of indolylquinones and...

Details Synthetic methods for the preparation of indolylquinones and... Synthetic methods for the preparation of indolylquinones and...

A - Human Necessities

61

K

A61K 31/40 (2006.01) A61K 31/404 (2006.01) C07D 209/02 (2006.01) C07D 209/12 (2006.01) C07D 209/42 (2006.01) C07D 403/08 (2006.01)

Patent

CA 2271737

The present invention relates to novel synthetic methods for the preparation of indolylquinones. The methods of the present invention are directed to synthetic reactions involving indoles and halo-quinones in solvent and in the presence of a metal carbonate. The invention also relates to bis- and mono- indolylquinones of high purity and pharmaceutical compositions containing the same.

La présente invention concerne de nouveaux procédés de synthèse permettant de préparer des indolylquinones. Lesdits procédés sont orientés vers des réactions de synthèse impliquant des indoles et des halo-quinones dans un solvant et en présence d'un carbonate métallique. La présente invention concerne également des mono- et des bis-indolylquinones de grande pureté et des compositions pharmaceutiques renfermant ces produits.

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