C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/705 (2006.01) A61K 39/00 (2006.01) A61K 47/48 (2006.01) C07K 14/135 (2006.01) C07K 14/15 (2006.01) C07K 14/47 (2006.01) G01N 33/566 (2006.01) G01N 33/574 (2006.01) F02B 75/02 (2006.01)
Patent
CA 2167730
The present invention relates to novel synthetic muc-1 peptides and muc-1 analogs comprising at least two 20-amino acid tandem repeats of muc-1, wherein said synthetic muc-1 peptide is capable of attaining native conformation in the absence of glycosylation. The invention also relates to methods of producing the peptides. The invention further relates to uses of the peptides, such as for vaccines and diagnostic testing.
L'invention concerne de nouveaux peptides synthétiques muc-1 et des analogues de muc-1 qui comportent au moins deux répétitions en tandem de 20 acides aminés de muc-1, où ce peptide synthétique muc-1 est capable de parvenir à une conformation native en l'absence de glycosylation. L'invention concerne aussi des procédés permettant de produire ces peptides, ainsi que certaines de leurs utilisations pour des vaccins et des diagnostics par exemple.
Finn Olivera J.
Fontenot J. Darrell
Montelaro Ronald C.
Finn Olivera J.
Fontenot J. Darrell
Montelaro Ronald C.
Na
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