Synthetic oligomers having phosphonate internucleosidyl...

Details Synthetic oligomers having phosphonate internucleosidyl... Synthetic oligomers having phosphonate internucleosidyl...

C - Chemistry, Metallurgy

07

H

C07H 21/00 (2006.01) A61K 31/7088 (2006.01) A61K 48/00 (2006.01) C07H 23/00 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2176498

Oligomers having phosphonate internucleosidyl linkages mixed with non-phosphonate internucleosidyl linkages which hybridize to RNA target sequences and methods for their preparation are provided.

L'invention concerne des oligomères comprenant des liaisons phosphonate internucléosidyle mélangées à des liaisons non phosphonate internucléosidyle s'hybridant avec des séquences d'ARN cibles, ainsi que leurs procédés de préparation.

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