Synthetic or natural peptides binding protein phosphatase...

Details Synthetic or natural peptides binding protein phosphatase... Synthetic or natural peptides binding protein phosphatase...

C - Chemistry, Metallurgy

07

K

C07K 14/16 (2006.01) A61K 38/16 (2006.01) A61K 38/45 (2006.01) A61K 38/46 (2006.01) A61P 31/12 (2006.01) A61P 33/00 (2006.01) C12N 9/12 (2006.01) C12N 9/16 (2006.01) C12N 15/48 (2006.01) C12N 15/54 (2006.01) C12N 15/55 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2455403

The invention concerns novel synthetic or natural peptides useful in particular for treating viral or parasitic infections or in the treatment of tumors, said peptides being less than 30 amino acids in size, preferably less than 20 amino acids, in particular 15 to 20 amino acids, and characterised in that they specifically bind, in vitro, a protein phosphatase 2A holoenzyme or one of its subunits. The invention also concerns a method for identifying such peptides, and their uses.

L 'invention a trait à de nouveaux peptides, synthétiques ou naturels utiles en particulier dans le traitement des infections virales ou parasitaires ou dans le traitement de tumeurs, lesdits peptides étant d'une taille inférieure à 30 acides aminés, de préférence inférieure à 20 acides aminés, notamment de 15 à 20 acides aminés, et caractérisés en ce qu'ils lient, in vitro, de manière spécifique, une holoenzyme protéine phosphatase de type 2A ou l'une de ses sous-unités. L'invention a aussi trait à une méthode d'identification de tels peptides, et à leurs utilisations.

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