Synthetic particulate vectors and process for their preparation

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/50 (2006.01) A23L 1/22 (2006.01) A61K 8/11 (2006.01) A61K 8/14 (2006.01) A61K 8/66 (2006.01) A61K 8/97 (2006.01) A61K 9/16 (2006.01) A61K 9/51 (2006.01) A61Q 19/00 (2006.01)

Patent

CA 2157384

A synthetic particulate vector comprising a non-liquid hydrophilic nucleus and an outer layer at least partially consisting of amphiphilic compounds and combined with the nucleus by hydrophobic interactions and/or ionic bonds. A method for preparing a particulate vector by encapsulating an ionizable active principle, vectors obtainable through said method, and pharmaceutical, cosmeticological or food compositions containing such vectors are also disclosed.

La présente invention a pour objet un vecteur particulaire synthétique, caractérisé en ce qu'il comporte: un noyau hydrophile non liquide, une couche externe constituée au moins en partie de composés amphiphiles, associée au noyau par des interactions hydrophobes et/ou des liaisons ioniques. Elle a également pour objet un procédé de préparation d'un vecteur particulaire par encapsulation d'un principe actif ionisable, ainsi que les vecteurs pouvant être obtenus par ce procédé. Elle concerne enfin des compositions pharmaceutiques, cosmétologiques ou à usage alimentaire contenant de tels vecteurs.

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