Synthetic peptide analogs for the treatment of cancer

A - Human Necessities – 61 – K

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Details

A61K 38/08 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2511446

The present invention relates to a combination of peptides that may be used for treatment of cancer. The peptide combination competes for the binding of specific neuropeptides at the plasma membrane and thereby alters the levels of key intracellular molecules implicated in cell proliferation, resulting in a broad spectrum of anticancer activity. The invention also relates to pharmaceutical compositions containing a combination of such peptide analogs.

La présente invention concerne une combinaison de peptides qui peut être utilisée pour traiter le cancer. La combinaison de peptides est en concurrence avec la liaison de neuropeptides spécifiques au niveau de la membrane plasmique, et modifie ainsi les taux de molécules intracellulaires clés impliquées dans la prolifération cellulaire, ce qui permet d'obtenir un large spectre d'activité anticancéreuse. L'invention a également pour objet des compositions pharmaceutiques contenant une combinaison d'analogues de peptides de ce type.

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