Synthetic peptide inhibitors of thrombin and thrombin...

Details Synthetic peptide inhibitors of thrombin and thrombin... Synthetic peptide inhibitors of thrombin and thrombin...

A - Human Necessities

61

K

A61K 38/08 (2006.01) C07K 7/06 (2006.01)

Patent

CA 2610496

The invention relates to synthetic peptide analogs of D-Arg-Oic-Pro-Gly-Phe and methods of their use to inhibit human platelet aggregation, thrombosis and cell activation mediated by PAR1 and PAR4.

L'invention concerne des analogues de peptides synthétiques de D-Arg-Oic-Pro-Gly-Phe et des procédés de leur utilisation visant à inhiber l'agrégation de plaquettes humaines, la thrombose et l'activation des cellules à médiation par PAR1 et PAR4.

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