Synthetic peptide lung surfactants having covalently bonded...

Details Synthetic peptide lung surfactants having covalently bonded... Synthetic peptide lung surfactants having covalently bonded...

C - Chemistry, Metallurgy

07

K

C07K 5/113 (2006.01) A61K 38/05 (2006.01) A61K 38/06 (2006.01) A61K 38/07 (2006.01) C07K 5/06 (2006.01) C07K 5/08 (2006.01) C07K 14/785 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2137348

Synthetic pulmonary surfactants having antioxidant properties consisting of a complex of a polypeptide of 3-4 amino acid residues, with an antioxidant moiety, and a lipid consisting of one or more of the lipids associated with natural pulmonary surfactant were prepared. These surfactants are useful in the treatment of respiratory distress syndrome.

Tensioactifs pulmonaires synthétiques à propriétés antioxydantes, qui sont constitués d'un complexe d'un polypeptide de restes d'acides amines 3-4, avec une fraction d'antioxydant, et d'un lipide constitué d'un ou plusieurs des lipides associés au tensioactif pulmonaire naturel. Lesdits tensioactifs sont utiles pour traiter le syndrome de la détresse respiratoire.

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