Synthetic peptide materials for joint reconstruction, repair...

Details Synthetic peptide materials for joint reconstruction, repair... Synthetic peptide materials for joint reconstruction, repair...

A - Human Necessities

61

K

A61K 38/17 (2006.01) A61K 38/39 (2006.01) A61L 27/22 (2006.01) A61P 19/02 (2006.01)

Patent

CA 2686895

In joint reconstruction, repair and cushioning applications, a synthetic polypeptide material is useful that contains cross-linked polypeptides that are modeled on human elastin or other fibrous proteins. The polypeptides comprise at least three consecutive beta-sheet/beta-turn structures and at least one amino acid residue that participates in cross-linking.

Dans des applications de reconstruction, de réparation et d'amortissement d'articulation, un matériau polypeptidique synthétique est utile. Ledit matériau contient des polypeptides réticulés modélisés sur de l'élastine humaine ou sur d'autres protéines fibreuses. Les polypeptides comprennent au moins trois structures consécutives de feuillet bêta/coude bêta et au moins un résidu d'acide aminé qui participe à la réticulation.

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