Synthetic peptides and methods of use for autoimmune disease...

Details Synthetic peptides and methods of use for autoimmune disease... Synthetic peptides and methods of use for autoimmune disease...

C - Chemistry, Metallurgy

07

K

C07K 5/00 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01) A61L 27/22 (2006.01) C07K 5/11 (2006.01) C07K 7/00 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/00 (2006.01) C07K 16/00 (2006.01) G01N 33/53 (2006.01) A61K 38/11 (2006.01)

Patent

CA 2336238

The invention provides heteropolymer compositions and peptide compositions, and methods of making and using therapeutic compositions comprising amino acid heteropolymers for treatment of a subject for an autoimmune or an inflammatory disease, the heteropolymer compositions made by solid state synthesis. The invention also provides kits for assaying binding of a composition to a water-soluble MHC protein.

L'invention concerne des compositions d'hétéropolymères et des compositions de peptides, ainsi que des procédés de fabrication et d'utilisation de compositions thérapeutiques renfermant des hétéropolymères d'acides aminés pour traiter un sujet atteint d'une maladie auto-immune ou inflammatoire, les compositions d'hétéropolymères étant fabriquées par synthèse à l'état solide. L'invention concerne également des trousses utiles pour tester la liaison d'une composition à une protéine du CMH soluble dans l'eau.

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