Synthetic peptides and vaccines against parvovirus

Details Synthetic peptides and vaccines against parvovirus Synthetic peptides and vaccines against parvovirus

C - Chemistry, Metallurgy

07

K

C07K 14/015 (2006.01) A61K 39/23 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2132742

The invention discloses synthetic peptides from autonomous parvoviruses, which are capable of inducing neutralizing antibodies against said viruses. These peptides correspond to antigenic sites located in the first 25 amino acids of the amino terminal end of the VP2 proteins of parvoviruses. Then these peptides are coupled to carrier proteins or to other immunogenic complexes, they can be used in the formulation of vaccines appropriate to protect animals against the infection caused by said parvoviruses.

L'invention concerne des peptides synthétiques contre les parvovirus autonomes, capables d'induire des anticorps neutralisants contre ces virus. Ces peptides correspondent à des sites antigéniques localisés dans les 25 premiers aminoacides de l'extrémité aminoterminale des protéines VP2 des parvovirus. Lorsque ces peptides s'accouplent à des protéines porteuses ou à d'autres complexes immunogéniques, ils peuvent être utilisés dans la formulation de vaccins appropriés à la protection d'animaux contre l'infection provoquée par ces parvovirus.

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