Synthetic peptides for an hiv-1 vaccine

Details Synthetic peptides for an hiv-1 vaccine Synthetic peptides for an hiv-1 vaccine

C - Chemistry, Metallurgy

07

K

C07K 14/16 (2006.01) A61K 39/21 (2006.01) C07K 19/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2053921

The invention discloses the identification, characterisation and use of a synthetic peptide, GPKEPFRDYVDRFYK (p24E), as a T-cell carrier for the appropriate assembly, with defined B-cell epitopes of the HIV-1 envelope protein, for the construction of potential synthetic vaccine candidates against HIV.

L'invention décrit l'identification, la caractérisation et l'utilisation d'un peptide synthétique GPKEPFRDYVDRFYK (p24E), comme porteur de lymphocites T pour l'assemblage approprié, avec des épitopes de lymphocites B définis de la protéine enveloppe de l'HIV-1, en vue de la construction de candidats de vaccins synthétiques potentiels contre l'HIV (virus de l'immunodéficience humaine).

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