Synthetic peptides for arterial imaging

Details Synthetic peptides for arterial imaging Synthetic peptides for arterial imaging

C - Chemistry, Metallurgy

07

K

C07K 14/78 (2006.01) A61K 38/17 (2006.01) A61K 38/39 (2006.01) A61K 49/00 (2006.01) A61K 49/04 (2006.01) A61K 49/14 (2006.01) A61K 51/08 (2006.01) C07K 4/12 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/775 (2006.01) A61K 38/00 (2006.01) A61K 49/02 (1990.01)

Patent

CA 2080493

2080493 9116919 PCTABS00008 Vascular disease including asymptomatic atherosclerosis can be diagnosed by administering a synthetic peptide or peptide analog having an affinity for, and propensity to accumulate at, a site of vascular injury to a patient, and then detecting the location of the peptide or peptide analog within the patient's vascular system. The synthetic peptide or peptide analog may include an amino acid sequence sufficiently duplicative of the amino acid sequence of a region of either the apolipoprotein B, apolipoprotein A-I, or elastin proteins such that the peptide or peptide analog accumulates at a site of vascular injury.

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