C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 7/08 (2006.01) C07K 7/50 (2006.01) C07K 7/64 (2006.01) C40B 40/10 (2006.01) G01N 33/543 (2006.01) G01N 33/564 (2006.01)
Patent
CA 2707870
Embodiments of the present invention relate to a three dimensional matrix of selected, synthetic peptide mimic sequences that are preferentially recognized by auto-antibodies, specifically by autoimmune antibodies, to be detected in patients afflicted with rheumatic arthritis, enabling enhanced sensitivity and specificity in detection of these antibodies in pre-symptomatic patients, in patients showing symptoms as well as patients confirmed positive for rheumatoid arthritis.
Cette invention concerne une matrice tridimensionnelle de séquences mimétiques peptidiques synthétiques choisies qui sont de préférence reconnues par des auto-anticorps, en particulier des anticorps auto-immuns, devant être détectés chez les patients atteints d'arthrite rhumatismale, la matrice permettant d'accroître la sensibilité et la spécificité de la détection de ces anticorps chez des patients présymptomatiques, chez des patients présentant des symptômes et chez des patients à polyarthrite rhumatoïde confirmée.
Lea Peter
Ling Mingfu
Heenan Blaikie Llp
Sqi Diagnostics Systems Inc.
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