Synthetic peptides specific for the detection of antibodies...

Details Synthetic peptides specific for the detection of antibodies... Synthetic peptides specific for the detection of antibodies...

C - Chemistry, Metallurgy

07

K

C07K 14/18 (2006.01) A61K 39/39 (2006.01) C07K 16/10 (2006.01) G01N 33/569 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2047792

The present invention relates to peptides which are immunoreactive to antibodies to HCV or NANBHV and a method of detecting the presence o~ HCV or NANBHV antibodies in body fluids by using the peptides as the antigen. The peptides are selected from both the envelope and non-structural protein regions of the HCV or NANBHV. The detection method includes enzyme linked immunosorbent assay or other immunoassay procedures. The peptides and conjugates or polymers thereof are also useful as immunogens in generating high titer antibodies to HCV or in vaccines.

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