Synthetic peptides which induce cellular immunity to the...

C - Chemistry – Metallurgy – 07 – K

Patent

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167/130, 530/7.1

C07K 7/08 (2006.01) A61K 39/21 (2006.01) C07K 14/155 (2006.01) C07K 14/16 (2006.01) A61K 39/00 (2006.01)

Patent

CA 1340896

This invention relates to the identification of short peptide segments of AIDS virus proteins which elicit T cellular immunity, and to a method of inducing cellular immunity to native proteins of the AIDS virus by immunization with short synthetic peptides. Five potential peptides have been identified by searching for regions which can fold as a maximally amphipathic helix. These may be useful to include in either a synthetic peptide- or recombinant fragment-based vaccine.

555480

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