Synthetic phospholipid compounds and their method of...

C - Chemistry – Metallurgy – 07 – F

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167/153, 167/321

C07F 9/10 (2006.01) A61K 9/08 (2006.01) A61K 9/127 (2006.01) A61K 47/24 (2006.01) C08G 65/335 (2006.01)

Patent

CA 1240692

ABSTRACT OF THE DISCLOSURE Synthetic phospholipid compounds are disclosed, which compounds are phosphatidylethanolamine polycarboxyl polyalkylene glycols. The compounds are prepared by the reaction of a phosphatidylethanolamine, a polycarboxylic acid, such as succinic or glutaryl anhydride, and a polyalkylene glycol, such as polyethylene glycol. The compounds are useful in solubilizing, in an aqueous environment, water-insoluble compounds.

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