C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/18 (2006.01) G01N 33/576 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2354152
Polypeptide that specifically binds to antibodies that specifically bind to human hepatitis C virus consisting of an antigenic sequence having specific immunoreactivity to the antibodies of SEQ ID NO:1, with the proviso that said polypeptide is different from SEQ ID NO:1, SEQ ID NO:2 and sequences resulting from the amputation of SEQ ID NO:1 with 1 to 10 amino acids from the N- terminal part and/or the C-terminal part of SEQ ID NO:1. Preferred polypeptides are selected from the group consisting of SEQ ID NO:8 through SEQ ID NO:18.
Cette invention concerne un polypeptide qui se lie spécifiquement à des anticorps, lesquels se lient spécifiquement au virus de l'hépatite C humain. Il consiste en une séquence antigénique présentant une immunoréactivité spécifique aux anticorps de SEQ ID NO:1, sous la réserve que ledit polypeptide soit différent de SEQ ID NO:1, SEQ ID NO:2 et des séquences résultant de l'amputation de SEQ ID NO:1 de 1 à 10 acides aminés de la partie N-terminal et/ou de la partie C-terminal de SEQ ID NO:1. Des polypeptides préférés sont sélectionnés dans le groupe composé de SEQ ID NO:8 à SEQ ID NO:18.
Dalbon Pascal
Jolivet Michel
Jolivet-Reynaud Colette
Bio Merieux
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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