Synthetic polypeptides for detecting mycobacterial infections

Details Synthetic polypeptides for detecting mycobacterial infections Synthetic polypeptides for detecting mycobacterial infections

C - Chemistry, Metallurgy

07

K

167/37, 530/7.04

C07K 7/08 (2006.01) A01K 39/04 (2006.01) C07K 14/35 (2006.01) G01N 33/68 (2006.01) A61K 39/00 (2006.01)

Patent

CA 1306582

ABSTRACT Antigens, immunogens, inocula, antibodies, diagnostic methods and systems relating to tuberculous mycobacteria are disclosed. Each of the compounds, compositions, methods or systems contains a synthetic polypeptide having about 13 or 14 to about 40 residues, or an antibody containing site that immunoreacts with such a polypeptide. The polypeptide includes the thirteen or fourteen amino acid reside sequence Image Image or Image Image . When linked to a carrier and introduced in an effective amount into a mammalian host, the polypeptide is capable of inducing productio of antibodies that immunoreact with an antigen to a tuberculous mycobacterium.

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