Synthetic process for an intermediate for ecteinascidin and...

Details Synthetic process for an intermediate for ecteinascidin and... Synthetic process for an intermediate for ecteinascidin and...

C - Chemistry, Metallurgy

07

D

C07D 498/18 (2006.01) C07D 491/18 (2006.01) C07D 491/22 (2006.01) C07F 7/18 (2006.01)

Patent

CA 2400614

An efficient process is described for the synthesis of 5, a key intermediate for the synthesis of the potent antitumor agents ecteinascidin 743 (1) and phthalascidin (2) from the readily available building blocks 3b and 4.

La présente invention concerne un procédé efficace permettant la synthèse du composé 5, un intermédiaire clé intervenant dans la synthèse des agents antitumoraux puissants ecteinascidine 743 (1) et phthalascidine (2) à partir des motifs structuraux faciles à obtenir 3b et 4.

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