Synthetic processes for the preparation of aminocyclohexyl...

Details Synthetic processes for the preparation of aminocyclohexyl... Synthetic processes for the preparation of aminocyclohexyl...

C - Chemistry, Metallurgy

07

D

C07D 207/12 (2006.01) C07C 235/14 (2006.01)

Patent

CA 2612375

This invention is directed to stereoselective synthesis of compounds of formula (I) or formula (II) or a pharmaceutically acceptable salt, ester, amide, complex, chelate, clathrate, solvate, polymorph, stereoisomer, metabolite or prodrug thereof; wherein R3, R4 and R5 are defined herein. Compounds of formula (I) and formula (II) are known to be useful in treating arrhythmias.

L'invention concerne la synthèse stéréosélective de composés de formule (I) ou de formule (II) ou d'un sel acceptable d'un point de vue pharmaceutique, d'un ester, d'un amide, d'un complexe, d'un chélate, d'un clathrate, d'un solvate, d'un polymorphe, d'un stéréoisomère, d'un métabolite ou d'un promédicament de ces composés; dans ces formules, R3, R4 et R5 étant tels que définis dans la demande. L'invention concerne également des composés de formule (I) et de formule (II) qui sont connus pour être utiles dans le traitement des arythmies.

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