Synthetic routes for the preparation of rhinovirus protease...

C - Chemistry – Metallurgy – 07 – D

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C07D 207/26 (2006.01) C07D 261/18 (2006.01) C07D 413/12 (2006.01) C07K 5/02 (2006.01)

Patent

CA 2376452

Efficient synthetic routes for the preparation of rhinovirus protease inhibitors of formula (I), as well as key intermediates usefull in those synthetic routes. These compounds of formula (I), as well as pharmaceutical compositions that contain these compounds, are suitable for treating patients or hosts infected with one or more picornaviruses.

La présente invention concerne des voies de synthèse efficaces qui sont utiles pour préparer des inhibiteurs de protéases de rhinovirus de formule (I) ainsi que des intermédiaires clés utilisés dans ces voies de synthèse. Les composés de formule (I) ainsi que des compositions pharmaceutiques contenant ces composés sont adaptés pour traiter des patients ou des hôtes infectés par un ou plusieurs picornavirus.

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