Synthetic urogastrone gene, corresponding plasmid...

C - Chemistry – Metallurgy – 12 – N

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195/1.2, 195/1.2

C12N 15/00 (2006.01) C07H 21/00 (2006.01) C07K 14/485 (2006.01) C12N 1/20 (2006.01) C12N 15/62 (2006.01) C12N 15/70 (2006.01)

Patent

CA 1197797

ABSTRACT "Synthetic urogastrone gene, corresponding plasmid recombinants, transformed cells, production thereof and urogastrone expression" A synthetic gene characterised in that it codes for the expression of urogastrone or a sub-unit thereof is disclosed. The production thereof by the assembly and ligation of a number of nucleotide blocks is also disclosed, as are corresponding plasmid recombinants, transformed cells and the production thereof. . The expression of urogastrone is further disclosed. Urogastrone is a polypeptide hormone (protein) which may be isolated in small amounts from human urine. It has an application in the treatment of ulcers and in the promotion of wound healing. The present invention provides a more viable commercial production.

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