Synthons for oligonucleotide synthesis

Details Synthons for oligonucleotide synthesis Synthons for oligonucleotide synthesis

C - Chemistry, Metallurgy

07

H

C07H 21/00 (2006.01)

Patent

CA 2421489

The present invention relates to phosphoramidite compounds, especially to a trivalent phosphorus multimer, a method of utilizing a trivalent phosphorus multimer to prepare an oligonucleotide, and a method of preparing a trivalent phosphorus multimer. In addition, the invention relates to a solid support that is derivatized with a trivalent phosphorus multimer and a method of preparing the same.

L'invention concerne des composé phosphoramidite, notamment un multimère phosphore trivalent, un procédé d'utilisation de celui aux fins de préparation d'oligonucléotides, ainsi qu'un procédé de préparation d'un tel multimère. De plus, l'invention concerne un support solide qui est dérivatisé au moyen d'un multimère phosphore trivalent et un procédé de préparation de celui-ci.

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