System and method for intravascular radiation therapy

A - Human Necessities – 61 – N

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A61N 5/10 (2006.01) A61M 25/01 (2006.01) A61M 25/10 (2006.01)

Patent

CA 2400416

A system for intravascular ionizing radiation therapy including a radiation device and a guide wire having radiopaque markers to facilitate precise repositioning of the radiation source along the length of the treatment site. The radiopaque markers are separated by a distance L, which corresponds to the distance between the 50 % dose points in the dose fall-off regions. This produces partial dose overlap when the radioactive source is positioned in tandem adjacent each radiopaque marker. Preferably, only the dose fall-off regions overlap thereby providing more uniform and complete radiation exposure along the length of the treatment site.

La présente invention concerne un système de radiothérapie ionisante intravasculaire comprenant un dispositif à rayonnement et un fil-guide équipé de marqueurs radio-opaques de façon à favoriser un repositionnement précis de la radiosource le long du site à traiter. Les marqueurs radio-opaques sont séparés les uns des autres d'une longueur L qui correspond à la distance entre 50% des points dose dans les régions de décroissance de la dose. Cela permet un chevauchement partiel des doses lorsque la radiosource est disposée en tandem contre chaque marqueur radio-opaque. De préférence, le chevauchement ne concerne que les régions de décroissance, ce qui permet une exposition plus uniforme et plus complète au rayonnement sur toute la longueur du site à traiter.

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