System for adaptive drug delivery

A - Human Necessities – 61 – M

Patent

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A61M 5/00 (2006.01)

Patent

CA 2554407

The present invention provides a system and method for determining and maintaining a concentration level of medication in a patient sufficient to achieve and maintain a desired effect on that patient. Generally speaking, in accordance with one embodiment of the invention, a medication delivery controller uses a patient response profile to determine a concentration of medication in the patient that will achieve the desired effect on the patient. The patient response profile is a graphical, tabular or analytical expression of the relationship between the concentration of a medication and the effect of the medication at the specific concentration. Using this information, the medication delivery controller provides instructions to a medication delivery unit such as, for example, an infusion pump or inhalation device, to deliver the medication to the patient at a rate that will achieve the desired concentration level of the medication in the patient.

L'invention concerne un système servant à déterminer et à maintenir un niveau de concentration de médicament chez un patient de façon suffisante pour obtenir et prolonger un effet désiré chez ce patient. De façon générale, selon un mode de réalisation de l'invention, un contrôleur d'administration de médicaments utilise un profil de réactions du patient afin de déterminer une concentration de médicament chez ce patient qui atteindra l'effet désiré chez ce dernier. Ce profil consiste en une expression graphique, tabulaire ou analytique du rapport entre la concentration du médicament et l'effet de celui-ci à la concentration spécifique. Cette information permet au contrôleur d'administration de médicament de transmettre des instructions à une unité d'administration de médicaments, telle que, par exemple, une pompe de perfusion ou un dispositif d'inhalation, de manière à administrer ce médicament au patient à un débit qui permettant d'obtenir le niveau de concentration désiré.

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