System for determining the stain quality of slides using...

Details System for determining the stain quality of slides using... System for determining the stain quality of slides using...

G - Physics

01

N

G01N 1/30 (2006.01) G01N 15/14 (2006.01) G06K 9/00 (2006.01)

Patent

CA 2525601

Systems for determining the stain quality of a plurality of biological specimens. A number of objects of interest are identified in a biological specimen. A first feature of each object of interest (e.g., nuclear area) and a second feature of each object of interest (e.g., nuclear integrated optical density) are measured, and a scatter plot of the first and second features is generated. The stain quality of the specimens are determined based on the spread of the distribution of points within the scatter plot.

La présente invention a trait à des systèmes permettant la détermination de la qualité de taches d'une pluralité de spécimens biologiques. On identifie un certain nombre d'objets d'intérêt dans un spécimen biologique. On effectue la mesure d'une première caractéristique de chaque objet d'intérêt (par exemple, la zone nucléaire) et d'une deuxième caractéristique de chaque objet d'intérêt (par exemple, la densité optique nucléaire, et la génération d'un diagramme de dispersion des première et deuxième caractéristiques. On détermine la qualité des taches des spécimens selon l'étalement de la distribution des points au sein du diagramme de dispersion.

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