System for electrophoretic stretching of biomolecules using...

Details System for electrophoretic stretching of biomolecules using... System for electrophoretic stretching of biomolecules using...

G - Physics

01

N

G01N 1/28 (2006.01)

Patent

CA 2682914

System for trapping and stretching biomolecules. A microfluidic device includes a symmetric channel forming a T-shaped junction at a narrow center region and three wider portions outside the center region. At least one power supply is provided to generate an electric potential across the T-shaped junction to create a local planar extensional field having a stagnation point in the junction whereby a biomolecule introduced into the microfluidic device is trapped at the stagnation point and stretched by the extensional field.

L'invention concerne un système de piégeage et d'étirement de biomolécules. Un dispositif microfluidique comprend un canal symétrique formant une jonction en forme de T au niveau d'une zone centrale étroite et de trois parties plus larges situées à l'extérieur de la zone centrale. Au moins une alimentation permet de générer un potentiel électrique sur la jonction en forme de T pour créer un champ d'extension plan local possédant un point de stagnation dans la jonction, tandis qu'une biomolécule introduite dans le dispositif microfluidique est piégée au niveau du point de stagnation et étirée par le champ d'extension.

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