System for enhancing cardiac signal sensing by cardiac...

Details System for enhancing cardiac signal sensing by cardiac... System for enhancing cardiac signal sensing by cardiac...

A - Human Necessities

61

K

A61K 48/00 (2006.01) A61K 38/17 (2006.01) A61M 5/14 (2006.01) A61N 1/362 (2006.01) A61P 9/00 (2006.01)

Patent

CA 2547967

The present invention provides delivery systems for delivering ion channel protein genetic material to cardiac cells in areas adjacent to where an electrode is to be positioned in a patient's heart to improve or correct the signal to noise ratio of cardiac signals, such as the P- wave. More specifically, there is provided a system for delivering sodium ion channel proteins or nucleic acid molecules encoding sodium ion channel proteins to a site in the heart adjacent to an electrode to increase the expression of the same, thereby enhancing the cardiac signal amplitude and enabling improved sensing of cardiac signals by an implanted pacemaker.

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