System for non-invasive measurement of glucose in humans

A - Human Necessities – 61 – B

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A61B 5/00 (2006.01) G01J 3/10 (2006.01) G01J 3/02 (2006.01)

Patent

CA 2445868

An apparatus and method for non-invasive measurement of glucose in human tissue by quantitative infrared spectroscopy to clinically relevant levels of precision and accuracy. The system includes six subsystems optimized to contend with the complexities of the tissue spectrum, high signal-to-noise ratio and photometric accuracy requirements, tissue sampling errors, calibration maintenance problems, and calibration transfer problems. The six subsystems include an illumination subsystem, a tissue sampling subsystem, a calibration maintenance subsystem, and FTIR spectrometer subsystem, a data acquisition subsystem, and a computing subsystem.

L'invention concerne un appareil et une méthode de mesure non effractive du glucose dans un tissu humain, au moyen d'une spectroscopie infrarouge quantitative à des niveaux de précision pertinents cliniquement. Ce système comprend six sous-systèmes optimisés pour rivaliser avec les complexités du spectre tissulaire, du rapport signal-bruit et des exigences de précision photométriques, avec les erreurs d'échantillonnage tissulaire, avec les problèmes de maintenance de l'étalonnage et avec les problèmes de transfert d'étalonnage. Ces six sous-systèmes comprennent un sous-système d'éclairage, un sous-système d'échantillonnage tissulaire, un sous-système de maintenance de l'étalonnage, un sous-système du spectromètre infrarouge à transformer de Fourrier (FTIR), un sous-système d'acquisition de données et un sous-système de calcul.

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