A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 51/00 (2006.01) A61K 36/14 (2006.01) C07K 16/00 (2006.01) C12P 21/08 (2006.01)
Patent
CA 2648099
The present invention provides a drug delivery system for targeted delivery of therapeutic agent-containing particles to tissues, cells, and intracellular compartments. The invention provides targeted particles comprising a particle, one or more targeting moieties, and one or more therapeutic agents to be delivered and pharmaceutical compositions comprising inventive targeted particles. The present invention provides methods of designing, manufacturing, and using inventive targeted particles and pharmaceutical compositions thereof.
La présente invention propose un système d'administration de médicament pour l'administration ciblée de particules contenant des agents thérapeutiques aux tissus, cellules et compartiments intracellulaires. L'invention propose des particules ciblées comportant une particule, une ou plusieurs fractions pouvant cibler, et un ou plusieurs agents thérapeutiques destinés à être administrés et des compositions pharmaceutiques comportant les particules ciblées de l'invention. La présente invention propose des procédés de conception, de fabrication, et d'utilisation des particules ciblées de l'invention et des compositions pharmaceutiques de celles-ci.
Cheng Jianjun
Farokhzad Omid C.
Langer Robert S.
Tepley Benjamin A.
Zale Stephen E.
Massachusetts Institute Of Technology
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
The Brigham And Women's Hospital Inc
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