Systemic delivery of serum stable plasmid lipid particles...

Details Systemic delivery of serum stable plasmid lipid particles... Systemic delivery of serum stable plasmid lipid particles...

A - Human Necessities

61

K

A61K 48/00 (2006.01) A61K 38/20 (2006.01) A61K 38/45 (2006.01) A61K 38/51 (2006.01) C12N 15/88 (2006.01)

Patent

CA 2321837

The present invention relates to methods and compositions for treating a neoplasia in a mammal with a therapeutic nucleic acid, such as a plasmid encoding an expressible gene, wherein the therapeutic nucleic acid is encapsulated in a lipid particle and administered at a site distal to the site of neoplasia, preferably intravenously, and delivered to the site of neoplasia by systemic delivery.

La présente invention porte sur des procédés et des compositions conçus pour traiter la néoplasie chez des mammifères.

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