Systems and methods for clot dissolution

Details Systems and methods for clot dissolution Systems and methods for clot dissolution

A - Human Necessities

61

B

A61B 17/22 (2006.01) A61M 5/00 (2006.01) A61M 25/00 (2006.01)

Patent

CA 2396727

Clot disruption and dissolution are achieved using a catheter (12) having both an agitator (30) and the ability to deliver a thrombolytic agent. The catheter (12) is introduced to a target region with a blood vessel and the agitator (30) manipulated to engage and disrupt a region of clot therein. The thrombolytic agent, such as tPA, streptokinase, or urokinase, is directly released into the clot at the point where the agitator (30) is engaging the clot. In this way, the thrombolytic activity of the agent is enhanced and the dissolution of the clot is improved.

Selon cette invention, on parvient à rompre et dissoudre des caillots au moyen d'un cathéter (12) doté d'un agitateur (30) et permettant d'administrer un agent thrombolytique. Le cathéter (12) est introduit dans une région cible pourvue d'un vaisseau sanguin et l'agitateur (30) vient en contact pour rompre une région du caillot. L'agent thrombolytique comme tPA, la streptokinase, ou l'urokinase, est directement libéré dans le caillot au point où l'agitateur (30) vient en contact avec le caillot. De cette façon, l'activité thrombolytique de l'agent est accrue et la dissolution du caillot améliorée.

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