Systems and methods for detecting toxins in a sample

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/02 (2006.01) C12M 1/34 (2006.01) G01N 33/18 (2006.01) G01P 13/00 (2006.01)

Patent

CA 2687690

In one aspect the invention provides a system for detecting the presence of toxins in a sample that includes a plurality of chambers for culturing organisms and observing the organism's motility response when introduced into a sample containing a toxin. The toxicity measurement system may include an imaging module to monitor and track the movement of one or more organisms in the sample and identify abnormalities. In other aspects, the invention provides methods of culturing organisms and detecting the presence of toxins in the sample using the motility response of organisms in the sample.

Selon l'un de ses aspects, l'invention concerne un système pour détecter la présence de toxines dans un échantillon comprenant une pluralité de chambres pour cultiver des organismes et observer la réponse en motilité de l'organisme quand il est introduit dans un échantillon contenant une toxine. Le système de mesure de la toxicité peut comprendre un module d'imagerie pour surveiller et suivre le mouvement d'un ou de plusieurs organismes dans l'échantillon et identifier les anomalies. Selon d'autres aspects, l'invention concerne des procédés pour cultiver des organismes et détecter la présence de toxines dans l'échantillon grâce à la réponse en motilité des organismes dans l'échantillon.

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