Systems and methods for identifying organ transplant risk

Details Systems and methods for identifying organ transplant risk Systems and methods for identifying organ transplant risk

G - Physics

01

N

G01N 33/554 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2486947

The present invention relates to methods of diagnosing and predicting organ transplant rejection. In particular, the present invention relates to the detection and prediction of kidney transplant rejection by detection of chemokines (e.g., CXCR3 and CCL chemokines) in urine. The present invention further relates to methods and compositions for assessing the efficacy of anti- rejection agents.

L'invention se rapporte à des procédés de diagnostic et de prédiction de rejet d'une greffe d'organe. En particulier, l'invention se rapporte à la détection et à la prédiction du rejet d'une greffe de rein par détection de chimiokines (p. ex. des chimiokines CXCR3 et CCL) dans l'urine. L'invention se rapporte également à des procédés et à des compositions assurant l'efficacité des agents anti-rejet.

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