A - Human Necessities – 61 – M
Patent
A - Human Necessities
61
M
A61M 1/38 (2006.01) A61M 1/36 (2006.01) B01D 21/26 (2006.01) B04B 5/00 (2006.01) B04B 5/04 (2006.01)
Patent
CA 2143829
Systems and methods for resuspending cellular- rich concentrates of blood are disclosed. Systems include first compartment (24) including a blood inlet port (40) and a plasma-rich platelets (PRP) collection port (38) and a red blood cell collection port (42), and second compartment (26) including a platelet-poor plasma (PPP) collection port (44) and a leukocyte-depleted PRP (LDPRP) inlet port (46), and a separation element (14). In resuspension mode, a volume of retained PPP is returned through the PPP collection port (44) into the second compartment (26) to mix with and and resuspend leukocyte-depleted platelet concentrate (LDPC) in the second compartment (26). During the resuspension period, a rotor (28) slowly oscillates the second compartment (26) first in one rotational direction and then in an opposite rotational direction. The oscillation creates variable agitation forces that aid the mixing and resuspension process within the second compartment (26).
L'invention concerne des systèmes et des procédés de remise en suspension de concentrés cellulaires riches du sang. Lesdits systèmes comportent un premier compartiment (24) présentant un orifice d'admission du sang (40), un orifice de collecte (38) de plaquettes riches en plasma (PRP) ainsi qu'un orifice de collecte de globules rouges (42), et un deuxième compartiment (26) présentant un orifice de collecte de plasma pauvre en plaquettes (PPP) (44) et un orifice d'admission de PRP (46) apauvri en leucocytes (LDPRP), ainsi qu'un élément de séparation. En mode de resuspension, un volume de PPP retenu est renvoyé dans le deuxième compartiment (26) par l'orifice de collecte de PPP pour être mélangé et remettre en suspension un concentré de plaquettes apauvri en leucocytes (LDPC) se trouvant dans le deuxième compartiment. Pendant la phase de remise en suspension, un rotor (28) fait lentement osciller le deuxième compartiment (26) d'abord dans un premier sens de rotation, puis dans le sens opposé. L'oscillation crée des forces d'agitation variables qui facilitent le processus de mélange et de remise en suspension dans le deuxième compartiment (26).
Baxter International Inc.
Sim & Mcburney
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