Systems and methods of microfluidic membraneless exchange...

Details Systems and methods of microfluidic membraneless exchange... Systems and methods of microfluidic membraneless exchange...

B - Operations, Transporting

01

D

B01D 61/24 (2006.01) A61K 35/14 (2006.01) A61M 1/38 (2006.01) B01D 61/28 (2006.01) C02F 1/44 (2006.01)

Patent

CA 2652173

A device, system and method for exchanging components between first and second fluids by direct contact in a microfluidic channel. The fluids flow as thin layers in the channel. One of the fluids is passed through a filter upon exiting the channel and is recycled through a secondary processor which changes the fluid's properties. The recycled fluid is reused for further exchange. The filter excludes blood cells from the recycled fluid and prevents or limits clogging of the filter. The secondary processor removes metabolic waste and water by diafiltration.

L'invention concerne un dispositif, un système et un procédé permettant d'échanger des composants entre un premier et un second fluide par contact direct dans un canal microfluidique. Les fluides s'écoulent sous forme de couches minces dans le canal. Un des fluides passe par un filtre lorsqu'il quitte le canal et est recyclé dans un transformateur secondaire qui modifie les propriétés du fluide. Le fluide recyclé est réutilisé pour d'autres échanges. Le filtre sépare les cellules sanguines du fluide recyclé et empêche ou limite le bouchage du filtre. Le transformateur secondaire élimine les déchets métaboliques et l'eau par diafiltration.

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