C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/31 (2006.01) C07K 14/195 (2006.01) C07K 19/00 (2006.01) C12N 15/74 (2006.01) C12P 21/02 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2435874
The present invention relates to nucleic acid molecules encoding outer membrane proteins and expression system for the expression of desired proteins and peptides in a methanotrophic bacterium, preferable the M. capsulatus. Further, the invention relates to the exportation and display of said peptides and proteins on the surface of said bacteria by fusion of the outer membrane protein with said peptides and proteins. The invention also describes a method for the production of a desired protein in the M. capsulatus.
L'invention concerne un système d'expression pour l'expression de protéines et de peptides dans une bactérie méthanotrophe, de préférence la bactérie M. capsulatus. En outre, l'invention concerne l'exportation et la présentation desdits peptides et protéines à la surface de ladite bactérie. Cette invention concerne également un procédé de production d'une protéine voulue dans la bactérie M. capsulatus.
Birkeland Nils Kare
Durkin A. Scott
Eidhammer Ingvar
Eisen Jonathan A.
Fraser Claire M.
Osler Hoskin & Harcourt Llp
Tigr
Unifob Stiftelsen Universitetsforskning I. Bergen
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