Systems, methods and compositions for optical stimulation of...

Details Systems, methods and compositions for optical stimulation of... Systems, methods and compositions for optical stimulation of...

C - Chemistry, Metallurgy

12

N

C12N 15/29 (2006.01) C07K 14/415 (2006.01) C12N 13/00 (2006.01) C12N 15/00 (2006.01) C12N 15/63 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2722278

Methods, systems and devices are implemented in connection with light- responsive ion channel molecules. One such method is implemented using a light- activated ion channel molecule that responds to a light stimulus. The method includes engineering the light-activated ion channel molecule in a cell; and activating the ion channel molecule, in response to light stimulus that is provided to the ion channel molecule and that has properties that do not activate a ChR2 ion channel, to allow ions to pass through the light-activated ion channel molecule.

Linvention concerne des procédés, systèmes et dispositifs mis en uvre en relation avec les molécules des canaux ioniques sensibles à la lumière. Un tel procédé est mis en uvre à laide dune molécule de canal ionique activée par la lumière répondant à un stimulus lumineux. Le procédé comprend la génération de la molécule de canal ionique activée par la lumière dans une cellule; et lactivation de ladite molécule de canal ionique en réaction au stimulus lumineux appliqué à ladite molécule de canal ionique et possédant des propriétés nactivant pas le canal ionique ChR2, pour permettre aux ions de passer à travers ladite molécule de canal ionique.

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