T-butyl ergoline derivatives

Details T-butyl ergoline derivatives T-butyl ergoline derivatives

C - Chemistry, Metallurgy

07

D

260/206.7

C07D 457/02 (2006.01) A61K 31/48 (2006.01)

Patent

CA 1339533

Ergoline derivatives of general formula I (see fig. I) wherein either R1 represents a hydrogen atom or a methoxy group and R2 represents a hydrogen atom or R1 and R2 taken together represent a chemical bond, and R3 represents a hydrogen atom, an unsubstituted or substituted nicotinoyl group or a 1-oxo-2-cyclopenten-3-yl group; or a pharmaceutically acceptable salt thereof are active at the Central Nervous System level and useful therefore in the treatment of cerebral insufficiency and senile dementia.

540338

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